THROMBOPROPHYLAXIS IN PATIENTS WITH PROSTATE TRANSURETHRAL RESECTION
Keywords:
enoxaparin, thromboprophylaxis, cancer pathologyAbstract
Background. Venous thromboembolism is a potentially life-threatening complication after surgical intervention, as well as in those with immobility after trauma or due to the presence of one or another pathology. Considering the importance of thromboprophylaxis and possible complications of its implementation authors conducted a study to prove the efficacy and safety of enoxaparin Flenox produced by “Farmak” company in oncology clinic. Materials and methods. The study included 59 patients who were divided into two groups by thromboprophylaxis type. All patients underwent transurethral resection-correction for prostate cancer, or laparotomic nephrectomy for kidney cancer. Results. The evaluation and analysis of data from patients on admission to hospital, indicators of coagulation (APTT, fibrinogen) and fibrinolytic systems (Ddimer) were within the reference values. When comparing these results, we noted the uniformity and comparability between groups. When analyzing the complications and side effects should be noted that using enoxaparin Flenox before surgery, intraoperative blood loss level was (235.5±32.0) ml, and there was no development of traumatic hematoma. With original enoxaparin the level of intraoperative blood loss was comparable (210.9±18.0) ml. Conclusions. The preoperative use of enoxaparin Flenox 6–12 hrs before surgery to influence the anti-coagulation properties of blood and the volume of blood loss during surgery, was comparable with the original enoxaparin introduction. It may be noted that Flenox enoxaparin thromboprophylaxis in patients requiring surgical intervention is effective and safe.
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