THE HEMOSTATIC SYSTEM IN PATIENTS WITH PURULENTINFLAMMATORY DISEASES OF THE PELVIC ORGANS
Keywords:
purulent-inflammatory diseases of the uterus, DIC-syndrome, hypercoagulationAbstract
Background. Inflammatory diseases of female genital organs occupy a leading place in the structure of gynecological diseases. Despite the expansion of diagnostic possibilities, synthesizing and applying new medication, the frequency of inflammatory diseases of the uterus and its appendages has no tendency to decrease. The Aim. Examine the state of the hemostatic system in patients with purulentinflammatory diseases of the pelvic organs and complications of pyo-inflammatory diseases of the pelvic organs and to offer an informative method for diagnosis of emerging hemocoagulation disorders. Materials and methods. There was carried out a comprehensive study of the dynamic state of the hemostatic system in 76 gynecological patients, undergoing tests and preparation for surgery for complications of chronic inflammatory diseases of the uterus. The Results. While studying the initial state of hemostasis, all patients were obtained coagulation indicators showing hypercoagulation. The presence of a hypercoagulation shows character of hemoviscosigram by increasing the activity of both vascular and platelet and procoagulant components of hemostasis. Parameter of the fibrinolytic activity — index of retraction and clot lysis — significantly reduced, indicating inhibition of fibrinolytic activity. Conclusions. In patients with purulent-inflammatory diseases of the uterus and complicated with purulent-inflammatory diseases of the uterus there is a violation of blood coagulation properties typical for DIC-syndrome chronic form stage I. Despite the conducted course of anti-inflammatory therapy in patients with preserved phenomena of endogenous intoxication, and therefore the dynamics of hemocoagulation disorders becomes typical for the DIC-syndrome chronic form stage I.
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