EFFECTS OF ANEMIA ON A COURSE OF EARLY POSTOPERATIVE PERIOD IN PATIENTS WITH REDUCED HEART OUTPUT SYNDROME AFTER CARDIAC SURGERY

Authors

  • I. M. Kuzmich
  • O. O. Tarabin
  • B. M. Todurov
  • M. G. Melnyk
  • O. V. Stanishevsky

DOI:

https://doi.org/10.31379/2411.2616.11.1.6

Keywords:

anemia, reduced heart output syndrome, tissue hypoxia, oxygen delivery, cardiac surgery

Abstract

Perioperative anemia in cardiac surgery patients is a cause of impaired oxygen delivery to peripheral tissues, which subsequently leads to development of tissue and organ hypoxia, and as logical conclusion, tissue and organ dysfunction. In patients who present signs of reduced heart output syndrome, correction of anemia is the only way of compensation of reduced oxygen delivery to body tissues. Results of this research indicate that patients presented with anemia had higher rates of adverse effects, such as: acute renal injury, neurologic complications, impairment of coagulation and respiratory complications. Compensation of hemodynamic instability/impairment and patients weaning from inotropic and mechanical support of circulation were more rapid and effective in patients with Hb levels more than 100 g/l. This data corresponds with that of world literature.

References

WHO/UNICEF/UNU. Iron deficiency anaemia. P. assessment, prevention, and control. Geneva, World Health Organization, 2011 (WHO/NHD/01.3).

Марино Пол Л. Интенсивная терапия. Москва, 2012. С. 29–40.

Implications and management of anemia in cardiac surgery. P. Current State of knowledge / Loor et al. The Journal of Thoracic and Cardiovascular surgery. 2012.

Risks of Anemia in Cardiac Surgery Patients / Lobel et al. Seminars in Cardiothoracic and Vascular Anesthesia. 2015.

Anemia and Patient Blood Management in Cardiac Surgery — Literature Review and Current Evidence / Dhir et al. Journals of Cardiothoracic and Vascular Anesthesia. 2017.

Anemia in cardiac surgery: next target for mortality and morbidity improvement? / Padmanabhan et al. Asian Cardiovascular and Thoracic Annals. 2016.

Risk associated with preoperative anemia in noncardiac surgery. P. a single-center cohort study / W. S. Beattie et al. Anesthesiology. 2009. Vol. 110 (3). P. 574–581.

Lowest hematocrit on bypass and adverse outcomes associated with coronary artery bypass grafting. Northern New England Cardiovascular Disease Study Group / G. R1 DeFoe et al. Ann Thorac Surg. 2001. Vol. 71 (3). P. 769–776.

Helms C. C. Mechanisms of hemolysis-associated platelet activation. J Thromb Haemost. 2013.

Duke W. W. The relation of blood platelets to hemorrhagic disease. JAMA. 1910. Vol. 60. P. 1185.

Ho C. H. The hemostatic effect of adequate red cell transfusion in patients with anemia and thrombocytopenia. Transfusion. 1996. Vol. 36. P. 290.

Wilfried W. H. Roeloffzen effects of red blood cells on hemostasis. Transfusion. 2010.

Near-wall excess of platelets induced by lateral migration of erythrocytes in flowing blood / W. S. Uijttewaal et al. Am J Physiol. 1993. Vol. 264. P. H1239–1244.

The effect of red blood cells on thrombin generation / M. K. Horne, III. et al. Br J Haematol. 2006. Vol. 133. P. 403–408.

Circulation. 2007 Jul 31. Vol. 116 (5). P. 471–479. Epub 2007 Jul 9.

Impact of preoperative anemia on outcome in patients undergoing coronary artery bypass graft surgery.

Investigators of the Multicenter Study of Perioperative Ischemia Research Group / A. 1. Kulier et al. Ischemia Research and Education Foundation.

Published

2022-02-14

How to Cite

Кузьмич, І. М., Тарабрін, О. О., Тодуров, Б. М., Мельник, М. Г., & Станішевський, О. В. (2022). EFFECTS OF ANEMIA ON A COURSE OF EARLY POSTOPERATIVE PERIOD IN PATIENTS WITH REDUCED HEART OUTPUT SYNDROME AFTER CARDIAC SURGERY. Clinical Anesthesiology and Intensive Care, (1), 14–22. https://doi.org/10.31379/2411.2616.11.1.6

Most read articles by the same author(s)

1 2 > >>