ANALYSIS OF THE PERIOPERATIVE STATE OF PATIENTS WITH SURGICAL AORTIC PATHOLOGY BASED ON A COMPARISON OF THE GENERAL FUNCTIONAL PARAMETERS OF THE ORGANISM
DOI:
https://doi.org/10.31379/2411.2616.13.1.11Keywords:
perioperative condition, surgical aortic pathology, meglumine sodium succinate, D-fructose-1,6-diphosphate sodium salt hydrateAbstract
The question of optimization of anesthetic support in patients with surgical correction of aortic pathology remains open, relevant. The purpose of our work was to analyze the perioperative state of patients with surgical pathology of the aorta based on a comparison of the general functional parameters of the organism. The basis of this study is the analysis of the results of the study in 118 patients with aortic surgery. Patients were divided into 2 groups based on the use of additional substances in the form of intensive care (IC) of additional substances. 46 patients were included in group I, which in addition to the IT algorithm a solution of meglumine sodium succinate (reamberine) was assigned, and 46 patients were included in the II group, which in addition to the IT algorithm was assigned a solution of D-fructose-1,6-diphosphate sodium hydrate salt (ezofosfina). The control group consisted of 26 patients who had surgical pathology of the aorta, according to all criteria, coincided with the patients in groups I and II, but had no additional substance in the IT. The patients’ status was determined on the basis of the EuroSCORE II postoperative mortality scale, the depth of anesthesia with a BIS monitor, the qualitative composition of the leukocyte formula, nasal and rectal temperature, blood composition, electrolyte levels, glucose, lactate, coagulogram, hemolysis and phosphate levels. Except a significant difference in phosphorus levels, we did not discriminate between the groups. It can be argued that supplementation with the intensive therapy in group I of sodium methluminium succinate solution and in the group II solution of D-fructose-1,6-diphosphate sodium hydrate salt do not significantly affect the leading functional parameters of the general condition of patients, but realize their mechanisms of action exclusively in relation to the interaction of the influence of hypoxia and the patient’s macroorganism.
References
H e Z. Remote ischemic preconditioning improves the cognitive function of elderly patients following colon surgery [Електронний ресурс] / Z.He, N.Xu, S.Qi // Medicine (Baltimor). – 2017. – Vol.96, №17. – e 6719. [Published online 2017 Apr 28] – Access mode: doi: 10.1097/MD.0000000000006719
Pathogenesis and treatment of post-operative cognitive dysfunction [Електронний ресурс] / M.Pappa, N.Theodosiadis, A.Tsounis [et al] // Electron Physician. – 2017. – Vol.9, №2. – P.3768-3775. [Published online 2017 Feb 25] – Access mode: doi: 10.19082/3768
Cognitive Dysfunction after Surgery: An Emergent Problem [Електронний ресурс] / G.Canistro, L.Levantesi, M.Oggiano [et al] // Journal of Alzheimer’s Disease & Parkinsonism. – 2017. – Vol.7. – P.304. [Accepted date: February 15, 2017; Published date: February 22, 2017] – Access mode: doi:10.4172/2161-0460.1000304
American Psychiatric Association. Diagnostic and statistical manual of mental disorders: DSM-5 Diagnostic Classification. – 5th ed. Arlington, VA: American Psychiatric Publishing; 2013. – Access mode: http://dsm.psychiatryonline.org/doi/book/10.1176/appi.books.9780890425596
Vahia V.N. Diagnostic and statistical manual of mental disorders 5: A quick glance / V.N.Vahia // Indian Journal of Psychiatry. – 2013. – Vol.55, №3. – P.220-223. – Access mode: doi: 10.4103/0019-5545.117131
Lu W. Development of Fast Neurotransmitter Synapses: general principles / W.Lu, Y.Chen // Brain Research Bulletin. – 2017. – Vol.129. – P.1-90.
Захаров В.В. Когнитивные нарушения при цереброваскулярных заболеваниях / В.В.Захаров, Н.В.Вахнина // Эффективная фармакология. – 2014. – №1. – С. 36-43.
Распространенность когнитивных нарушений при неврологических заболеваниях (анализ работы специализированного амбулаторного приема) / Н.Н.Яхно, И.С.Преображенская, В.В.Захаров [и др.] // Неврология, нейропсихиатрия, психосоматика. – 2012. – №2. – С.30-34.
