THE INITIAL STATE AND RESERVE CAPABILITIES OF THE SYSTEM OF HEMOSTASIS IN PATIENTS WITH UTERINE MYOMA
Keywords:
uterine cancer, disorders of hemostasis, the perioperative periodAbstract
Background. Hemostatic disorders have been found by many researchers in patients with uterine myoma because, which is often the cause of thrombohemorrhagic complications in the perioperative stage of treatment. Aim. To analyze the current state of the problem of hemostasis in patients with uterine myoma patients based on a review of existing adaptation mechanisms. Materials and methods. There was carried out a complex dynamic investigation of the hemostatic system during the surgical treatment of 92 gynecological patients — a study group and 30 women who had routine inspection — the control group. Blood clotting system was investigated by instrumental diagnostic method — lowfrequency pyezoelectric thromboelastography. Results. Hemostatic system in patients with uterine myoma before treatment has certain differences compared with the control group: hyperaggregation as increasing intensity of the contact phase of coagulation at 76 % (p <0.05), hypercoagulation in the form of increased intensity of coagulation drive at 71 % (p<0.05) and the activation of fibrinolysis — the growth of the index of retraction and clot lysis by 65 % (p<0,05). Conclusions. Hemostatic disorders in patients with uterine fibroids often lead to complications in the perioperative thrombohemorrhagic stage of treatment, hence the need for a rational choice of anesthetic management, prevention and intensive therapy of hemostatic disorders in the perioperative stage of treatment.
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