PERSONALIZED CORRECTION OF DISORDERS OF HEMOSTASIS SYSTEM IN PATIENTS WITH COVID-19 AT THE INPATIENT AND OUTPATIENT STAGES

Authors

  • O.O. Tarabrin
  • I.I. Tyutryn
  • O.H. Shytykova
  • D.S. Slyzevych
  • Ye.A. Borzov
  • V.F. Klimenkova
  • S.V. Zyryanov
  • V.V. Udut
  • R.Ye. Sukhonos

DOI:

https://doi.org/10.31379/2411.2616.18.2.10

Keywords:

COVID-19, thromboelastography, hemostasis

Abstract

The article describes violations of the hemostasis system in patients in the acute period of COVID-19 and at the stage of convalescence, as well as methods of targeted correction of the identified violations. Prevention of serious complications of COVID-19 infection requires complex assess of the hemostasis system and prompt correction of identified disorders. The method of piezothromboelastography (PTEG) allows for a comprehensive and informative assessment of the functional state of the hemostasis system and monitoring the effectiveness of therapy, both in the hospital and on an outpatient basis. For assessment of anticoagulant therapy authors used t3 and ICD (the intensity of coagulation drive) parameters of PTEG. Assessment of anti-platelet and vasoprotective therapy requires of control of t1 и CTA (a constant thrombin activity). And correction of fibrinolytic activity was evaluated through control of CIP (the clot intensity of the polymerization), t5, indicators. Monitoring of effectiveness and personal approach for correction of hemostasiological disorders allows decrease the risks of complications.

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Published

2022-04-26

How to Cite

Тарабрін, О., Тютрин, І., Шитикова, О., Слизевич, Д., Борзов, Є., Кліменкова, В., Зирянов, С., Удут, В., & Сухонос, Р. (2022). PERSONALIZED CORRECTION OF DISORDERS OF HEMOSTASIS SYSTEM IN PATIENTS WITH COVID-19 AT THE INPATIENT AND OUTPATIENT STAGES. Clinical Anesthesiology and Intensive Care, (2), 79–87. https://doi.org/10.31379/2411.2616.18.2.10

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